Clinical Scientist (NHS)

Research Associate/Physicist – Department of Radiology – University of Cambridge

Clinical Scientist – Medical Physics Department, Addenbrooke’s Hospital, Cambridge University Hospitals NHS Foundation Trust

Speciality: Magnetic Resonance Image analysis and data analysis

Email: G Andrew   Tel.: +44 (0)1223 256255

Profile

Andrew Gill graduated in Natural Sciences and Computer Science in 1993 from the University of Cambridge. After working in the commercial sector as a software engineer he re-trained as a Clinical Scientist at Addenbrooke’s Hospital in Cambridge from 2006-10, whilst studying for an MSc in Radiation Physics at UCL. His PhD studies were subsequently undertaken part-time at the University of Cambridge.

His PhD research interests involved the analysis of dynamic contrast-enhanced MR images using pharmacokinetic (PK) modelling to produce perfusion parameter maps of tumours. This work looked in particular at biomarkers of treatment response in tumours, temporal resolution requirements for successful PK model application and the repeatability of PK model analysis for DCE-MRI in tumours.

Concurrently with his PhD study he provided research MR physics support to Papworth Hospital NHS Foundation Trust, specialising in thoracic imaging and data analysis.

He has recently joined Dr Ferdia Gallagher’s group in the Department of Radiology, Cambridge as Image Analyst, with a particular focus on hyperpolarized 13C imaging.

Professional Education

Current Research

Hyperpolarized 13C – Image analysis

Dynamic contrast-enhanced (DCE-) MRI – Pharmacokinetic modelling Thoracic MRI

Main Collaborators

Dr Ferdia Gallagher, Cambridge Radiology

Professor David J Lomas, Cambridge Radiology

Dr Martin Graves, Cambridge Radiology

Dr Nicholas Screaton, Papworth Radiology

Dr Nagmi Qureshi, Papworth Radiology

Last 5 Publications

Carbonic Anhydrase Activity Monitored In Vivo by Hyperpolarized 13C-Magnetic Resonance Spectroscopy Demonstrates Its Importance for pH Regulation in Tumors.

Gallagher, F. A., Sladen, H., Kettunen, M. I., Serrao, E. M., Rodrigues, T. B., Wright, A.,  Brindle, K. M. (2015).

Cancer Res, 75(19), 4109-4118. doi:10.1158/0008-5472.CAN-15-0857

The use of error-category mapping in pharmacokinetic model analysis of dynamic contrast-enhanced MRI data.

Gill, A. B., Anandappa, G., Patterson, A. J., Priest, A. N., Graves, M. J., Janowitz, T., Lomas, D. J. (2015).

Magn Reson Imaging, 33(2), 246-251. doi:10.1016/j.mri.2014.10.010

An investigation into the effects of temporal resolution on hepatic dynamic contrast-enhanced MRI in volunteers and in patients with hepatocellular carcinoma.

Gill, A. B., Black, R. T., Bowden, D. J., Priest, A. N., Graves, M. J., & Lomas, D. J. (2014).

Phys Med Biol, 59(12), 3187-3200. doi:10.1088/0031-9155/59/12/3187

DCE and DW MRI in monitoring response to androgen deprivation therapy in patients with prostate cancer: a feasibility study

*Barrett T., *Gill, A. B., Kataoka, M. Y., Priest, A. N., Joubert, I., McLean, M. A., Graves, M. J., Stearn, S., Lomas, D. J., Griffiths, J. R., Neal, D., Gnanapragasam, V. J., and Sala, E. Magn Reson Med, 2012.  67(3):p. 778-85.

(*Joint first authors)

Ex vivo study of carotid endarterectomy specimens: quantitative relaxation times within atherosclerotic plaque tissues.

Degnan, A. J., Young, V. E. , Tang, T. Y., Gill, A. B., Graves, M. J., Gillard, J. H., and Patterson, A. J.

Magn Reson Imaging, 2012. 30(7):p. 1017-21

Advanced ovarian cancer: multiparametric MR imaging demonstrates response- and metastasis-specific effects.

Sala, E., Kataoka, M. Y., Priest, A. N., Gill, A. B., McLean, M. A., Joubert, I., Graves, M. J., Crawford, R. A., Jimenez-Linan, M., Earl, H. M., Hodgkin, C., Griffths, J. R., Lomas, D. J., and Brenton, J. D.

Radiology, 2012. 263(1):p. 149-59.