Department of Radiology, University of Cambridge School of Clinical Medicine.
Neuroradiology Fellow and PhD student
Contact: Email: N Sheikh-Bahaei Tel.: + 44 (0)1223 336892
Diagnosis of Alzheimer’s disease at the early stages is challenging and requires various tests. In our current project (PEMA study) we are looking at finding less expensive and more available imaging techniques than are currently used in day to day practice for diagnosis of Alzheimer’s disease. We image each participant with two PET scans: one to measure amyloid deposition (a brain protein known to acculumate in excessive amounts in those with, or at risk of, Alzheimer’s disease) and the other to find areas of low brain activity (reduced activity in the brain is also a known change in Alzheimer’s disease). The findings of PET scans will then be used to evaluate MRI techniques. If our data support a clear relation between PET and MRI findings, this new MRI method could be used as a safer, cheaper and more available alternative to nuclear imaging (PET scans).
We hope by adding these new MRI techniques to the routine protocol of Alzheimer’s imaging, we can not only introduce methods for early diagnosis of Alzheimer’s disease but also provide non-invasive valuable follow up techniques to assess the disease behaviour over time.